Amyotrophic lateral sclerosis (ALS) is a devastating, uniformly lethal progressive degenerative disorder of motor neurons that overlaps with frontotemporal lobar degeneration (FTLD) clinically, morphologically, and genetically.Although many distinct mutations in various genes are known to cause amyotrophic lateral sclerosis, it remains poorly under
BackgroundRheumatic heart disease (RHD) poses a major disease burden among disadvantaged populations globally.It results from acute rheumatic fever (ARF), a complication of Group A Streptococcal (GAS) infection.These conditions are acknowledged as diseases of poverty, however the role of specific social and environmental factors in GAS infection an
Background: Globally, a significant hike in the prevalence of overweight and obesity has been found in almost all age groups.Aims: To determine the prevalence of obesity among adults in a rural area of Pondicherry and to study the risk predictors of obesity in the study population.Materials & Methods: A cross-sectional descriptive study was conduct
Theoretical models aimed at explaining the evolution of honest, informative begging signals employed by nestling birds to solicit food from their parents, require that dishonest signalers incur a net viability cost in order to prevent runaway escalation of signal intensity over evolutionary time.Previous attempts Ignition to determine such a cost e
BolA is a ubiquitous global transcription factor.Despite its clear role in the Purses induction of important stress-resistant physiological changes and its recent implication in the virulence of Salmonella, further research is required to shed light on the pathways modulated by BolA.In this study, we resorted to untargeted 1H-NMR metabolomics to un